XVIII. Symposium der GTFCh, 17. - 20. April 2013 in Mosbach

 GTFCh   

 

Tagungspräsident: Thomas Krämer

Institut für Rechtsmedizin, Universität Zürich, Schweiz

 

Wissenschaftliches Komitee: Georg Schmitt, Gisela Skopp

Institut für Rechtsmedizin und Verkehrsmedizin, Heidelberg

Tagungszentrum: Alte Mälzerei, Alte Bergsteige 7, Mosbach (Baden)

 

 

Mittwoch, 17. April 2013

 

20:00 Uhr       Mittwochsvortrag für die Mosbacher Öffentlichkeit

 

                        „Neues, Erwartetes und Unerwartetes aus der Dopinganalytik“

Prof. Dr. Mario Thevis, Deutsche Sporthochschule Köln

 

 

Donnerstag, 18. April 2013

 

Satellitensymposium

 

 

Gesellschaftlicher Umgang mit Drogenabhängigkeit:
Zwangsentzug, Zurückstellung der Strafvollstreckung, akzeptanzbasierte Ansätze, Safer Party, Drug-Checking, Heroingestützte Behandlung, verkehrsmedizinische und analytische Aspekte

 

14:00 Uhr   Eröffnung und Begrüßung / Opening and welcome

 

Richter Bernd Weidig (Landgericht Saarbrücken)
Realität des Alkohol- und Drogenkonsumenten aus Sicht der Rechtsprechung (Zwangsentzug, Bestrafungsrückstellung)


Alexander Bücheli (Jugendberatung Streetwork, Zürich, Schweiz)
Die Wirkung macht es aus! Gesellschaftliche Realität des Drogenkonsums am Beispiel einer akzeptanzbasierten Drogenberatung in Zürich


Dr. Hans-Jörg Helmlin (Kantonsapothekeramt, Bern, Schweiz)
HPLC on the dance floor - Führt mobiles Drug-Checking wirklich zu Safer-Party?


Dr. Thilo Beck, (Arud - Zentren für Suchtmedizin, Zürich, Schweiz)
Heroingestützte Behandlung von Opiatabhängigen – Eine pragmatische Annäherung anhand des Schweizer Modells

 

Dr. Bruno Liniger (Institut für Rechtsmedizin, Zürich, Schweiz)
Fahrfähigkeit/Fahreignung bei Patienten in der Substitutionsbehandlung


Prof. Dr. Frank Musshoff, (Institut für Rechtsmedizin, Bonn)
Forensisch toxikologische Aspekte der Heroinsubstitution


Raymond Niesink, (Trimbos Instituut, Utrecht, Niederlande)
Drug policy in The Netherlands

 

 

18:00 Uhr       Sitzungsende / End of session

 

 

Die GTFCh dankt

Thermo Fisher Scientific

und dem Bund gegen Alkohol und Drogen im Straßenverkehr e.V. (BADS)

für die großzügige Unterstützung des Satellitensymposiums.

 

Freitag, den 19. April 2013

 

Symposium

 

 

09:00 Uhr       Eröffnung des Symposiums und Grußworte / Opening of the symposium and welcome

 

09:10 Uhr                   Vorträge: Trockenblutproben / Legal highs / Oral presentations: Dried blood spots / Legal highs

 

V01                 Manuel Rusconi, Magali Dovat Sabatella, Frank Sporkert, Lausanne /Schweiz)
Stability investigations of phosphatidylethanol (PEth) on dried blood spots

V02                 Ana Hernandez Redondo, Lars Ambach, Stephan Lanz, Anita Iannone, Wolfgang Weinmann, Bern (Schweiz)

                        Analysis of designer stimulants in dried blood spots by LC-MS/MS

                       

V03                 Marion Schäffer, Michael Pütz, Ralf Zimmermann, Neuherberg, Rostock, Wiesbaden

                        Application of comprehensive two-dimensional gas chromatography for the assessment of the presence of Damiana in legal highs

 

V04                 Marek Dziadosz, Jens-Peter Weller, Michael Klintschar, Jörg Teske, Hannover

                        Combined analysis of synthetic cannabinoids and other designer drugs

 

V05                 Patrick Dahm, Melanie Hutter, Olexander Schuster, Stefan Kneisel, Voler Auwärter, Freiburg

                        Synthesis of two monohydroxylated metabolites of the synthetic cannabinoid JWH-122 and comparison with authentic urine samples

 

V06                 Hans-Christian Rudloff, Bjoern Moosmann, Volker Auwärter, Merja Neukamm, Freiburg

                        Synthetic cannabinoids: Development of a smoke machine and analysis of main-stream and side-stream smoke condensates

 

V07                 Merja Neukamm, Melanie Hutter, Bjoern Moosmann, Patrick Dahm, Hans-Christian Rudloff, Volker Auwärter, Freiburg

                        Synthetic cannabinoids in hair – contribution of contamination by side-stream smoke

 

V08                 Lisa Redlingshöfer, Melanie Hutter, Volker Auwärter, Freiburg

                        In vitro investigations on the metabolism of synthetic cannabinoids

 

V09                 Volker Auwärter, Melanie Hutter, Stefan Kneisel, Bela Szabo, Siegfried Knasmüller, Verena Koller, Illka Ojanperä, Bernd Werse, Cornelia Morgenstern, Michael Pütz, Christoph Härtel, Renate Lind-Krämer, Michal Kidawa, Teemu Gunnar, Lars Ambach, Wolfgang Weinmann, Freiburg, Wien (Österreich), Helsinki (Finnland), Frankfurt, Wiesbaden, Warschau, Bern (Schweiz)

                        The EU project ‘SPICE and synthetic cannabinoids’: Summary of the key findings

 

11:00 Uhr       Kaffeepause / Coffee break

 

11:30 Uhr       Vorträge: Hochauflösende Massenspektrometrie / Oral presentations: High
                        resolution mass spectrometry

 

V10                 Markus Meyer, Andreas Helfer, Hans Maurer, Homburg (Saar)
Fast, simple, and validated LC-HR-MS/MS assay for identification and quantification of drugs in human blood plasma often requested in context of brain death diagnosis

 

V11                 Markus Meyer, Martina Bach, Michael Bovens, Alain Turcant, Hans Maurer, Homburg (Saar), Zürich (Schweiz), Angers (Frankreich)
Methoxetamine: Metabolism and detectability of a novel ketamine analog – studied by GC-MS, LC-MSn, and LC-HR-MSn

 

V12                 Markus Meyer, Tina Braun, Carina Wink, Alain Turcant, Hans Maurer, Homburg (Saar), Angers (Frankreich)
Studies on the metabolism and detectability of the phenethylamine-derived designer drug 2C-P in rat and human urine using GC-MS, LC-MSn, and LC-HR-MS/MS

 

V13                 Jessica Welter, Markus Meyer, Pierce Kavanagh, Hans Maurer, Homburg (Saar), Dublin (Irland)
Studies on the metabolism and the detectability of 4-methyl-amphetamine and its isomers 2-methyl-amphetamine, and 3-methyl-amphetamine in rat urine using GC-MS, LC-MSn, and LC-HR-MSn

 

V14                 Andreas Roemmelt, Andrea Schwaninger, Thomas Kraemer, Zürich (Schweiz)
Validated quantification of 35 antidepressants in whole blood by targeted data extraction of the MS/MS spectra generated by data independent acquisition (SWATH) as part of a simultaneous screening and quantification procedure

 

12:30 Uhr       Mittagspause / Lunch break

 

13:30 Uhr       Posterausstellung mit Kaffeetheke / Poster session and coffee bar

 

P01                              Martin Weber, Holger Schulz, Munster
Determination of warfare agents (nerve agents, blister agents, saxitoxin, and ricin) in food, water and on materials and articles

 

P02                  Paul Elsinghorst, Horst Thiermann, Marianne Koller, München
Verification of chemical warfare agent exposure in human samples

 

P03                  Laura Huppertz, Stefan Kneisel, Volker Auwärter, Jürgen Kempf, Freiburg
Trapping ‘Spice’: A comprehensive, automated LC-ion trap-MS screening approach for the detection of currently 38 synthetic cannabinoids in serum.

 

P04                  Melanie Hutter, Lisa Redlingshöfer, Volker Auwärter, Freiburg
LC-MS/MS based method for the detection and partial quantification of the major metabolites of 15 synthetic cannabinoids in human urine samples

 

P05                  Stefan König, Anja Kaiser, Andreas Längin, Thomas Wüthrich, Wolfgang Weinmann, Bern (Schweiz)
New LC-MS/MS methods for JWHs’, ethyl glucuronide and benzodiazepines based on two dimensional chromatography

 

P06                  Laura Huppertz, Susanne Vogt, Jürgen Kempf, Freiburg
An automated MSn-based screening procedure for clinical and forensic toxicology

 

 

P07                  Andreas Thomas, Sven Guddat, Wilhelm Schänzer, Mario Thevis, Köln
Application of nano-scale electrospray ionisation in LC-MS for small molecules in comparison to established techniques

 

P08                  Oliver Temme, Oliver Lerch, Gernot Brauers, Thomas Daldrup, Düsseldorf, Mülheim (Ruhr)
Extensive automation of the SPE-GC/MS analysis of opiates, cocaine, their metabolites and methadone from serum and other matrices

 

P09                  Johannes Zagermann, Bauke Albada, Evelyn Pawlik, Hellmut Mahler, Düsseldorf, Bochum
N-Pentylindole: A marker for the detection of synthetic cannabinoids

 

P10                  Golo Meyer, Markus Meyer, Hans Maurer, Homburg (Saar)
Studies on the metabolism and detectability of xylazine in rat and human urine using GC-MS, LC-MSn, and LC-HR-MSn

 

P11                  Pirkko Kriikku, Lars Wilhelm, Stefan Jenckel, Janne Rintatalo, Jukka Hurme, Jan Kramer, Helsinki (Finnland), Geesthacht, Vantaa (Finnland), Lübeck
Ethanol concentrations in breath and blood of drunk drivers; results from hand-held breathalyzer devices vs. analysis of venous blood samples

 

P12                  Marcel Grapp, Herbert Desel, Wolfgang Grellner, Göttingen
Validation of an alcohol dehydrogenase method for forensic blood alcohol determination on Thermo Scientific Indiko analyzer and comparison with Technikon autoanalyzer

 

P13                  Bernd Diehl, Elina Zailer, Köln, Rheinbach
Alternative method for blood alcohol determination by proton -NMR - Development and validation -

 

P14                  Verena Angerer, Volker Auwärter, Freiburg
Development and validation of a method for congener analysis in serum and application to a pilot experiment addressing endogenous 1-propanol

 

P15                  Gernot Brauers, Irina Steiner, Patricia Klaka, Thomas Daldrup, Düsseldorf
Quantification of the biogenic phenethylamine alkaloid hordenine by LC-MS/MS in beer

 

P16                  Nicole Schwab, Gisela Skopp, Heidelberg
A preliminary investigation on the influence of flavonoids on ethyl glucuronide formation

 

P17                  Julia Krüger, Inge Herrle, Matthias Graw, Hans Sachs, Gabriele Roider, München
Analysis of morphine and codeine in dried blood on a carpet

 

P18                  Heike Wollersen, Victoria Spencer, Freidoon Erdmann, Reinhard Dettmeyer, Giessen
Three unusual cases of CO poisoning with each two victims

 

P19                  Stefanie Lottner-Nau, Birgit Övgüer, Liane Paul, Matthias Graw, Hans Sachs, Gabriele Roider, München
Abuse of pregabalin - Results of the postmortem toxicology from 2010 to 2012

 

P20                  Andreas Bauer, Jutta Schöpfer, Hans Sachs, Matthias Graw, Gabriele Roider, München
Fatality after intake of methylone, MDMA and amphetamine: a case report

 

P21                  Susanne Vogt, Volker Auwärter, Annette Thierauf, Freiburg
Discovery of two corpses after lethal intoxication by oral application of transdermal fentanyl patches

 

P22                  Stefanie Iwersen-Bergmann, Hilke Jungen, Alexander Müller, Hilke Andresen-Streichert, Lennart Muras, Axel Heinemann, Hamburg
Drug-related deaths in Hamburg

 

P23                  Alexandra Schröck, Yvonne Hari, Stefan König, Thomas Wüthrich, Volker Auwärter, Annette Thierauf, Wolfgang Weinmann, Bern (Schweiz), Freiburg

                        Pharmacokinetics of GHB and detection window in serum and urine after single uptake of a low dose of GBL

 

P24                  Elke Below, Britta Bockholdt, Giovanni Talarico, Greifswald
Regular cannabis users in road traffic – a result of insufficient monitoring?!

 

P25                  Ricarda Kegler, Andreas Büttner, Jörg Nowotnik, Gernot Rücker, Daniel Rentsch, Rostock
Trends of drug consumption at the music festival FUSION 2009-2012

 

P26                  Kerstin Boomgarden-Brandes, Niels Tobias, John Koc, Hans Sachs, Bernd Mühlbauer, Bremen, München
From palm to hair: Transmissibility of methadone and its metabolite EDDP

 

P27                  Bjoern Moosmann, Nadine Roth, Volker Auwärter, Freiburg
Hair analysis for THCA-A, THC and CBN after handling cannabis plant material

 

P28                  Markus Baumgartner, Georg Staubli, Thomas Kraemer, Zürich (Schweiz)
Detection of midazolam in children’s hair after one dose for a procedure in anaesthesia

 

P29                  Luc Kirchen, Michel Yegles, Luxembourg (Luxemburg)
Influence of hair straightening on ethyl glucuronide content in hair

 

P30                  Volker Dangel, Rudolf Alkier, Manfred Möller, Stuttgart
Detection of illicit drugs in meconium to assess neonatal abstinence syndrome (NAS)

 

P31                  Susanne Lott, Frank Musshoff, Burkhard Madea, Bonn

                        LC/MS/MS method of 6-MAM, Morphine, Morphine-3-glucuronide and Morphine-6-glucuronide for quantitative analysis in serum

 

P32                       Georg Schmitt, Gisela Skopp, Heidelberg
                        Quality control charts for internal quality control of forensic blood alcohol analysis

 

P33                  Michael Herbold, Georg Schmitt, Gisela Skopp, Heidelberg, Walldorf

                        A comparison of data evaluation from proficiency tests performed according either to Horwitz or DIN ISO 13528

 

14:00 Uhr       Treffen der Kolleginnen und Kollegen im Ruhestand in der „Tenne“ / Meeting of retired colleagues in the „Tenne“

 

Liane Paul, München
            Zum EU-Projekt Druid: Auswirkungen auf die Praxis am Beispiel / EU-project       DRUID: Practical impacts by reference to an example

 

14:30 Uhr       Vorträge: Illegale Herstellung von Drogen / Alternative Untersuchungsmaterialien / Oral presentations: Clandestine production / Alternative matrices

 

V15                 Lars Müller, Nathalie Martin, Thorsten Rößler, Michael Pütz, Wiesbaden

                        APAAN – A new precursor substance for the illicit production of amphetamine

 

V16                 Michael Pütz, Nathalie Martin, Nina Boxen, Jan Rittgen, Thorsten Rössler, Sabine Schneiders, Wiesbaden, Idstein

                        Forensic trace and comparative analysis related to clandestine amphetamine laboratories

 

V17                 Oliver Temme, Jolien Diepstra, Gernot Brauers, Thomas Daldrup, Düsseldorf
Lyophilization of post mortem material for long term storage

 

V18                 Cornelius Hess, Frank Musshoff, Burkhard Madea, Köln

                        Detection of diabetic metabolism disorders post mortem – case reports

 

V19                 Tina Binz, Milena Madry, Markus Baumgartner, Thomas Kraemer, Zürich (Schweiz)
A novel method for the analysis of ethyl glucuronide (EtG) in nails by LC/LC-ESI-MS/MS with column switching technique

 

V20                 Milena Madry, Andrea Schwaninger, Markus Baumgartner, Thomas Kraemer, Zürich (Schweiz)
Systematic investigation of the incorporation of zolpidem in fingernails after a single dose

 

V21                 Yvonne Hari, Stefan König, Alexandra Schröck, Patrizia Coro, Volker Auwärter, Anette Thierauf, Wolfgang Weinmann, Bern (Schweiz), Freiburg
LC-MS/MS of GHB in head hair and beard

 

V22                 Michael Poetzsch, Andrea Schwaninger, Cedric Hysek, Matthias Liechti, Thomas Kraemer, Zürich, Basel (Schweiz)
Ultrafast high throughput quantification of methylphenidate and MDMA in oral fluid using MALDI-triple quadrupole mass spectrometry

 

 

16:00 Uhr       Mitgliederversammlung / Business Meeting

 

 

Samstag, 20. April 2013

 

9:00 Uhr         Falldarstellungen und freie Themen aus der Forensischen Chemie und Toxikologie / Case reports – communications in forensic chemistry and toxicology

V23                 Deborah Montenarh, Markus Hopf, Stefan Warth, Hans Maurer, Peter Schmidt, Andreas Ewald, Homburg (Saar)
Development of an LC-MS/MS approach for screening and identification of benzodiazepines, z-drugs, antidepressants, neuroleptics, PDE-5 inhibitors, opioids and new synthetic drugs in human hair and urine samples

 

V24                 Gernot Brauers, Oliver Temme, Irina Steiner, Thomas Daldrup, Düsseldorf

                        UV-spectroscopy and LC-MS/MS - An advantageous combination for multi target screening in forensic toxicology

 

V25                 Markus Meyer, Sandra Maurer, Julia Dinger, Golo Meyer, Birgit Klein, Folker Westphal, Hans Maurer, Homburg (Saar), Wiesbaden, Kiel

                        Metabolism and toxicological detection of the new pyrrolidinophenone designer drug 3’,4’-methylenedioxy-alpha-pyrrolidinobutyrophenone (MDPBP) in rat and human urine using GC-MS and LC-MSn

 

V26                 Florian Pitterl, Sebastian Köb, Johanna Pitterle, Birthe Schubert, Kathrin Libiseller, Herbert Oberacher, Innsbruck (Österreich)
Comprehensive systematic toxicological analysis of human body fluids by simultaneous LC/MS/MS and GC/MS analysis

 

V27                 Jan Schäper, Susanna Fehn, Folker Westphal, München, Kiel
Designer-drug 5-IT – a fatal case

 

V28                 Nadine Schaefer, Benjamin Peters, Dietmar Bregel, Stefan Kneisel, Volker Auwärter, Peter Schmidt, Andreas Ewald, Homburg (Saar), Freiburg
A fatal case involving several synthetic cannabinoids

 

V29                 Gertrud Rochholz, Lars Radünz, Katharina Bornemann, Kiel
Analysis of remifentanil in cases of lethal intoxication

 

V30                 Ricarda Jantos, Gisela Skopp, Heidelberg
Postmortem blood and tissue concentrations of R- and S-enantiomers of methadone and its metabolite EDDP

 

V31                 Birgit Reiter, Kurt Jiran, Thomas Stimpfl, Wien (Österreich)
Practical considerations for the reliable quantification in postmortem specimens

 

V32                 Cornelius Hess, Natalie Ritke, Sebastian Broecker, Hauke Ruehs, Frank Musshoff, Burkhard Madea, Bonn, Berlin
Metabolism, pharmakokinetics and urinary excretion of levamisole and its metabolite aminorex

 

10:30 Uhr       Kaffee-Pause / Coffee Break

 

11:00 Uhr       Fortsetzung / Continuation

 

V33                 Anna Suhr, Jorge Martinez-Ramirez, Daniela Remane, Polina Mattis, Christoph Sauer, Ursula Standke, Frank Peters, Jena, Erfurt
Studies on the metabolism of five designer drugs by the fungus Cunninghamella bertholletiae using LC-MS/MS and GC-MS analysis

 

V34                 Jorge Martinez-Ramirez, Juliane Strien, Juliane Sanft, Gita Mall, Grit Walther, Frank Peters, Jena, Bogota (Kolumbien), Utrecht (Niederlande)
Isolation of fungi from postmortem samples, DNA-based identification of the species, and studies on their capability of metabolizing five model drugs

 

V35                 Victoria Spencer, Esra Ergin, Heike Wollersen, Nico Erdmann, Gießen, Aachen
Salvia divinorum - An attempt to explain different effects based on the origin

 

V36                 Nico Erdmann, Esra Ergin, Heike Wollersen, Victoria Spencer, Aachen, Gießen
A convenient method for Salvia divinorum analyses

 

V37                 Marco Diestelmann, Anna Zangl, Daniela Schmidt-Thomé, Inge Herrle, Eva Walser, Matthias Graw, Liane Paul, München
Findings on MDPV (Methylenedioxypyrovalerone) in routine cases from 2010 to 2012

 

V38                 Sarah Hangartner, Franz Dussy, Thomas Briellmann, Basel (Schweiz)
Can we obtain information from urine about resent cannabis consumption in DRUID cases?

 

V39                 Hilke Jungen, Hilke Andresen-Streichert, Alexander Müller, Stefanie Iwersen-Bergmann, Hamburg
Analysis of disaccharides in urine samples of opioid users. Are carbohydrates suitable markers to determine intravenous abuse of methadone and buprenorphine?

 

12:50 Uhr       Schlusswort zum Symposium / Closing words

 

13:00 Uhr       Tagungsende / End of the meeting

 

Für die Unterstützung des Hauptsymposiums dankt die GTFCh folgenden Firmen, die auch auf der Industrieausstellung vertreten sind und ihre neuesten Produkte zu unserem Fachgebiet präsentieren:

 

AB Sciex Deutschland

ACQ Science

Agilent Technologies

Axel Semerau

Bruker Daltonik

Chromsystems Instruments & Chemicals

ERC

Gerstel

Gilson International

Greiner Bio-One International

LGC Standards

Mahsan Diagnostika

Mavand Solutions

Medichem

Mettler Toledo

nal von minden

Phenomenex

Recipe Chemicals & Instruments

Shimadzu Europa

Sigma-Aldrich

Thermo Fisher Scientific

Waters

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